Which of the following is NOT a cause of hypoalbuminemia?

Hypoalbuminemia refers to a condition where there is a low level of albumin in the blood, often indicating an underlying health issue. Each of the listed conditions can lead to hypoalbuminemia, except for hyperthyroidism.

Hyperthyroidism is characterized by an overproduction of thyroid hormones, which can increase metabolism and affect various bodily functions. While it can lead to changes in protein metabolism, it is not commonly associated with decreased production of albumin or excess loss of it in the urine, which are primary factors contributing to hypoalbuminemia.

Malignancy, burns, and liver disease, on the other hand, are directly related to hypoalbuminemia. Malignancy can lead to malnutrition or alter protein synthesis. Burns can result in significant protein loss through damaged skin. Liver disease severely affects albumin production since the liver is responsible for synthesizing this protein.

Understanding the specific mechanisms of each condition helps clarify why hyperthyroidism does not typically cause hypoalbuminemia, distinguishing it from the other options that lead to reduced albumin levels in the circulation.