Which of the following is NOT a symptom of von Gierke's Disease?

Prepare for the ASCP Technologist in Chemistry (C) Exam. Use flashcards and multiple choice questions, each with hints and explanations. Be exam ready!

Von Gierke's Disease, or Glycogen Storage Disease Type I, is characterized by a deficiency in the enzyme glucose-6-phosphatase, which is crucial for the conversion of glycogen to glucose. This inadequate conversion leads to a buildup of glycogen in the liver and kidneys and associated metabolic complications.

The condition typically manifests with several symptoms due to the body's inability to maintain normal blood glucose levels during fasting. Hypoglycemia is a prominent symptom, as patients cannot release glucose into the bloodstream effectively. Fatty liver, another common symptom, occurs due to excessive glycogen and fat accumulation in liver cells, ultimately leading to hepatomegaly. Additionally, hyperlipidemia is observed since the metabolism of fatty acids is also affected, causing elevated lipid levels in the blood.

Inheritance patterns for von Gierke's Disease are autosomal recessive rather than autosomal dominant. This means that the disease typically arises when both copies of the gene (one inherited from each parent) are mutated. Autosomal dominant inheritance would imply that only one mutated copy of the gene is sufficient to cause the disease, which does not apply to von Gierke's Disease. Therefore, identifying the inheritance pattern as autosomal dominant is not a symptom of the

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