Which enzyme is known to be depressed in cases of liver disease?

In cases of liver disease, pseudcholinesterase levels are known to be depressed. This enzyme is produced primarily in the liver, and its activity can significantly decrease when liver function is impaired, as seen in conditions such as cirrhosis or hepatitis. Measuring pseudcholinesterase levels can therefore serve as an important marker for assessing liver function and the extent of hepatic damage.

While other enzymes such as amylase, creatine kinase, and lactate dehydrogenase can be involved in various pathological conditions, they do not specifically reflect liver function to the same extent as pseudcholinesterase. For example, amylase is primarily associated with pancreatic function and gastrointestinal issues, creatine kinase is related mainly to muscle or cardiac tissue damage, and lactate dehydrogenase can be elevated in a range of conditions, not just those affecting the liver. Therefore, the specific depression of pseudcholinesterase serves as a more direct indicator of liver dysfunction.