What HDL level is associated with a higher risk for coronary artery disease?

High-density lipoprotein (HDL) cholesterol is often referred to as "good" cholesterol due to its role in transporting cholesterol away from the arteries and back to the liver, where it can be processed and eliminated. Generally, higher levels of HDL are associated with a lower risk of coronary artery disease (CAD).

A level of HDL cholesterol that is less than or equal to 40 mg/dL is considered low and has been linked to an increased risk of CAD. Lower HDL levels fail to adequately remove cholesterol from the arteries, allowing for the potential accumulation of plaque and subsequent cardiovascular issues. This threshold is significant because it helps stratify patients into different risk categories regarding heart disease.

In contrast, levels of HDL cholesterol that are 40 mg/dL or greater are typically viewed as being protective against coronary artery disease, with even higher levels (like 60 mg/dL or above) further reducing risk. Therefore, identifying and managing low levels of HDL cholesterol is crucial in assessing cardiovascular health.