What compound may interfere with lipase testing, resulting in false elevations?

In lipase testing, triglycerides are particularly relevant because they can lead to false elevations in lipase activity measurements. When the level of triglycerides is markedly elevated in a patient's serum, it may inhibit the accurate measurement of lipase due to interference with the assay's methodology. High concentrations of triglycerides can produce a turbidity effect, which might obscure the results or lead to inaccuracies in enzyme activity estimation.

In contrast, cholesterol and diglycerides do not have the same level of interference with lipase assays. Cholesterol does not typically play a significant role in lipase activity; it is primarily associated with lipid transport and metabolism, rather than enzyme interference. Diglycerides, while also fatty substances, do not have the same propensity to interfere with lipase assays as triglycerides do.

As a result, triglycerides are the primary concern when testing for lipase, and understanding their potential to falsely elevate levels is crucial in interpreting lipase test results properly.