At what bilirubin level is UV light treatment typically initiated for neonates?

Bilirubin is a substance produced from the breakdown of red blood cells and is typically processed by the liver. In neonates, particularly in the first few days of life, it is common for bilirubin levels to rise due to the immature liver function. However, elevated bilirubin can lead to jaundice and, if severe, can cause serious complications, including kernicterus (a type of brain damage).

Phototherapy, or UV light treatment, is a common intervention for managing elevated bilirubin levels in newborns. The initiation of phototherapy is generally recommended when bilirubin levels reach a certain threshold to prevent potential complications.

When bilirubin levels are greater than or equal to 15 mg/dL, the risk of hyperbilirubinemia increases significantly, and initiating phototherapy at this level is considered an appropriate clinical practice. The mechanism of phototherapy involves the conversion of bilirubin into water-soluble isomers that can be more easily excreted by the infant's body.

While other levels may prompt monitoring or minor interventions, the threshold of 15 mg/dL is widely recognized in clinical guidelines as the point at which phototherapy should be started to effectively manage the risk associated with significantly elevated bilirubin levels. This makes it the