Which dye is most specific for albumin measurement?

Bromcresol purple (BCP) is the dye that is most specific for albumin measurement. This dye is commonly used in laboratory assays due to its selective binding properties with albumin, resulting in a color change that can be quantitatively measured. The pH sensitivity of bromcresol purple allows for effective albumin detection at physiological pH ranges, making it an ideal choice for serum albumin assays.

In contrast, other dyes do not offer the same specificity for albumin. For instance, phenol red is used in various applications but is not specific to albumin; rather, it serves as a general pH indicator. Brilliant blue can interact with different proteins, leading to less specificity for albumin, while neutral red is generally used in cell staining rather than in protein assays. Thus, bromcresol purple stands out as the optimal choice due to its specific interaction with albumin, enhancing the accuracy of its measurement in clinical chemistry.