True or False? Assaying both amylase and lipase increases diagnostic sensitivity.

Assaying both amylase and lipase indeed increases diagnostic sensitivity, particularly in the context of pancreatitis and other pancreatic disorders. Amylase is an enzyme that helps in the digestion of carbohydrates, while lipase is specialized in the digestion of fats. When assessing potential pancreatic damage or disease, measuring both enzymes can provide more comprehensive information.

In cases of acute pancreatitis, it has been observed that lipase levels typically rise more significantly and remain elevated longer than amylase levels, making lipase a more specific marker for pancreatic inflammation. However, in certain conditions, amylase may also be elevated due to factors like salivary gland disorders or other gastrointestinal issues.

By testing both enzymes, healthcare providers can better differentiate between these conditions and enhance the sensitivity of the diagnosis. This combination of assays can help identify the underlying cause of symptoms more effectively than if only one were measured. Therefore, assaying both amylase and lipase is beneficial for increasing the diagnostic accuracy in evaluating pancreatic or related abdominal pathologies.